Subsequent to the completion of the Human Genome Project advances in genomic sequencing have led to a dramatic fall in time taken and cost to produce very large scale, high throughput sequence-based (HTS) datasets. Cambridge University and the cluster of closely-connected research Institutes in the region have a long and productive history in both the development and application of DNA sequencing technologies.

The creation of the Eastern Sequence and Informatics Hub (EASIH) based on major funding from the MRC, University of Cambridge and the NIHR Cambridge Biomedical Research Centre, will enable researchers working in our region to utilise a crucial 21st-century research approach in their studies. In collaboration with the nearby European Bioinformatics Institute, an international centre for sequence data analysis, EASIH will also provide researchers with access to the tools and protocols required to analyse these complicated and large-scale datsets, and in the design and implementation of projects.

EASIH, based at the Cambridge University Addenbrooke's Hospital, has a research development and strategic aim to apply HTS to routine medical diagnostic uses, in particular in HLA typing in transplantation and cord blood stem cells, and re-sequencing of disease genes in collaboration with NHS Blood and Transplant and NHS Regional Clinical Genetics Services.

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EASIH
University of Cambridge
Level 4, Laboratory Block Box 268
Addenbrooke's Hospital
Cambridge
CB2 0QQ
UK

Tel: +44 (0)1223 746768
Fax: +44 (0)1223 746777
Email: enquiries@easih.ac.uk